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Estimating the Precursor Frequency of Naive Antigen-specific CD8 T Cells
The constraint of fitting a diverse repertoire of antigen specificities in a limited total population of lymphocytes results in the frequency of naive cells specific for any given antigen (defined as the precursor frequency) being below the limit of detection by direct measurement. We have estimated...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2193761/ https://ncbi.nlm.nih.gov/pubmed/11877489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20001021 |
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