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A strategy to discover decoy chemokine ligands with an anti-inflammatory activity
Excessive signaling by chemokines has been associated with chronic inflammation or cancer, thus attracting substantial attention as promising therapeutic targets. Inspired by chemokine-clearing molecules shaped by pathogens to escape the immune system, we designed a generic screening assay to discov...
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| Publicado en: | Sci Rep |
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| Autores principales: | , , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4595804/ https://ncbi.nlm.nih.gov/pubmed/26442456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14746 |
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