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An Antedrug of the CXCL12 Neutraligand Blocks Experimental Allergic Asthma without Systemic Effect in Mice

The chemokine receptor CXCR4 and its chemokine CXCL12 are involved in normal tissue patterning but also in tumor cell growth and survival as well as in the recruitment of immune and inflammatory cells, as successfully demonstrated using agents that block either CXCL12 or CXCR4. In order to achieve s...

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Main Authors: Daubeuf, François, Hachet-Haas, Muriel, Gizzi, Patrick, Gasparik, Vincent, Bonnet, Dominique, Utard, Valérie, Hibert, Marcel, Frossard, Nelly, Galzi, Jean-Luc
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2013
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636874/
https://ncbi.nlm.nih.gov/pubmed/23449983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.449348
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