Targeted sequencing reveals clonal genetic changes in the progression of early lung neoplasms and paired circulating DNA

Lungs resected for adenocarcinomas often harbour minute discrete foci of cytologically atypical pneumocyte proliferations designated as atypical adenomatous hyperplasia (AAH). Evidence suggests that AAH represents an initial step in the progression to adenocarcinoma in situ (AIS), minimally invasive...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Izumchenko, Evgeny, Chang, Xiaofei, Brait, Mariana, Fertig, Elana, Kagohara, Luciane T., Bedi, Atul, Marchionni, Luigi, Agrawal, Nishant, Ravi, Rajani, Jones, Sian, Hoque, Mohammad O., Westra, William H., Sidransky, David
Format: Artigo
Langue:Inglês
Publié: Nature Pub. Group 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4595648/
https://ncbi.nlm.nih.gov/pubmed/26374070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9258
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