MDR1/ABCB1 gene polymorphisms in patients with chronic myeloid leukemia

BACKGROUND: Tyrosine kinase inhibitors (TKIs) are the recommended treatment for patients with chronic myeloid leukemia (CML). The MDR1/ABCB1 gene plays a role in resistance to a wide spectrum of drugs, including TKIs. However, the association of MDR1/ABCB1 gene polymorphisms (SNPs) such as C1236T, G...

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Detalhes bibliográficos
Publicado no:Blood Res
Main Authors: Lardo, Mabel, Castro, Marcelo, Moiraghi, Beatriz, Rojas, Francisca, Borda, Natalia, Rey, Jorge A, Lazarowski, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society of Hematology; Korean Society of Blood and Marrow Transplantation; Korean Society of Pediatric Hematology-Oncology; Korean Society on Thrombosis and Hemostasis 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4595581/
https://ncbi.nlm.nih.gov/pubmed/26457282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5045/br.2015.50.3.154
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