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Searching for polymorphisms that affect gene expression and mRNA processing: Example ABCB1 (MDR1)
Cis-acting genetic variations can affect the amount and structure of mRNA/protein. Genomic surveys indicate that polymorphisms affecting transcription and mRNA processing, including splicing and turnover, may account for main share of genetic factors in human phenotypic variability; however, most of...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer-Verlag
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2761059/ https://ncbi.nlm.nih.gov/pubmed/17025270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/aapsj080361 |
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