EP4 Receptor–Associated Protein in Macrophages Ameliorates Colitis and Colitis-Associated Tumorigenesis

Prostaglandin E(2) plays important roles in the maintenance of colonic homeostasis. The recently identified prostaglandin E receptor (EP) 4–associated protein (EPRAP) is essential for an anti-inflammatory function of EP4 signaling in macrophages in vitro. To investigate the in vivo roles of EPRAP, w...

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Vydáno v:PLoS Genet
Hlavní autoři: Nakatsuji, Masato, Minami, Manabu, Seno, Hiroshi, Yasui, Mika, Komekado, Hideyuki, Higuchi, Sei, Fujikawa, Risako, Nakanishi, Yuki, Fukuda, Akihisa, Kawada, Kenji, Sakai, Yoshiharu, Kita, Toru, Libby, Peter, Ikeuchi, Hiroki, Yokode, Masayuki, Chiba, Tsutomu
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4595503/
https://ncbi.nlm.nih.gov/pubmed/26439841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005542
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