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Intranasal administration of poly-gamma glutamate induced antiviral activity and protective immune responses against H1N1 influenza A virus infection

BACKGROUND: The global outbreak of a novel swine-origin strain of the 2009 H1N1 influenza A virus and the sudden, worldwide increase in oseltamivir-resistant H1N1 influenza A viruses highlight the urgent need for novel antiviral therapy. METHODS: Here, we investigated the antiviral efficacy of poly-...

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Publicat a:Virol J
Autors principals: Kim, Eun-Ha, Choi, Young-Ki, Kim, Chul-Joong, Sung, Moon-Hee, Poo, Haryoung
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4595321/
https://ncbi.nlm.nih.gov/pubmed/26437715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-015-0387-0
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