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Butylidenephthalide antagonizes cromakalim-induced systolic pressure reduction in conscious normotensive rats

BACKGROUND: Butylidenephthalide (Bdph), a main constituent of Ligusticum chuanxiong Hort., was reported to have selective antianginal effect without changing blood pressure in conscious rat. Recently, we have observed that Bdph antagonized cromakalim, an ATP-dependent K(+) channel opener, in guinea-...

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Detalhes bibliográficos
Publicado no:BMC Complement Altern Med
Main Authors: Shih, Chung-Hung, Lin, Yu-Jing, Chen, Chi-Ming, Ko, Wun-Chang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4594919/
https://ncbi.nlm.nih.gov/pubmed/26438097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12906-015-0877-z
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