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Butylidenephthalide Blocks Potassium Channels and Enhances Basal Tension in Isolated Guinea-Pig Trachea

Butylidenephthalide (Bdph, 30~300 μM), a constituent of Ligusticum chuanxiong Hort., significantly enhanced tension in isolated guinea-pig trachea. In this study, we investigate the mechanism(s) of Bdph-induced contraction in the tissue. Isolated trachea was bathed in 5 mL of Krebs solution containi...

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Detalhes bibliográficos
Main Authors: Hsu, Hsin-Te, Yang, You-Lan, Chen, Wan-Chen, Chen, Chi-Ming, Ko, Wun-Chang
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119919/
https://ncbi.nlm.nih.gov/pubmed/25114927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/875230
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