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Beyond Standard Therapy: Drugs Under Investigation for The Treatment of Gastrointestinal Stromal Tumor

INTRODUCTION: Gastrointestinal stromal tumor (GIST) is the most common non-epithelial malignancy of the GI tract. With the discovery of KIT and later PDGFRA gain-of-function mutations as factors in the pathogenesis of the disease, GIST was the quintessential model for targeted therapy. Despite the s...

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Detalhes bibliográficos
Publicado no:Expert Opin Investig Drugs
Main Authors: Alturkmani, Hani J, Pessetto, Ziyan Y, Godwin, Andrew K
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4594857/
https://ncbi.nlm.nih.gov/pubmed/26098203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/13543784.2015.1046594
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