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Evaluating new therapies in gastrointestinal stromal tumor using in vivo molecular optical imaging
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors in the US. The majority (~85%) of GISTs possess gain-of-function mutations in KIT or PDGFRA, causing constitutive activation of the kinase receptor. GIST management has been transformed by the identification of tumor driv...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4100992/ https://ncbi.nlm.nih.gov/pubmed/24755645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.28880 |
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