Evaluating new therapies in gastrointestinal stromal tumor using in vivo molecular optical imaging

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors in the US. The majority (~85%) of GISTs possess gain-of-function mutations in KIT or PDGFRA, causing constitutive activation of the kinase receptor. GIST management has been transformed by the identification of tumor driv...

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Autors principals: Hensley, Harvey, Devarajan, Karthik, Johnson, James R, Piwnica-Worms, David, Godwin, Andrew K, von Mehren, Margaret, Rink, Lori
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2014
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4100992/
https://ncbi.nlm.nih.gov/pubmed/24755645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.28880
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