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Neomycin and pentagalloyl glucose enhanced cross-linking for elastin and glycosaminoglycans preservation in bioprosthetic heart valves

Glutaraldehyde cross-linked bioprosthetic heart valves fail within 12–15 years of implantation due to limited durability. Glutaraldehyde does not adequately stabilize extracellular matrix components such as glycosaminoglycans and elastin, and loss of these components could be a major cause of degene...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Biomater Appl
Hauptverfasser: Tripi, Daniel R, Vyavahare, Naren R
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4594843/
https://ncbi.nlm.nih.gov/pubmed/24371208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0885328213479047
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