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Neomycin and pentagalloyl glucose enhanced cross-linking for elastin and glycosaminoglycans preservation in bioprosthetic heart valves

Glutaraldehyde cross-linked bioprosthetic heart valves fail within 12–15 years of implantation due to limited durability. Glutaraldehyde does not adequately stabilize extracellular matrix components such as glycosaminoglycans and elastin, and loss of these components could be a major cause of degene...

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Publicat a:J Biomater Appl
Autors principals: Tripi, Daniel R, Vyavahare, Naren R
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4594843/
https://ncbi.nlm.nih.gov/pubmed/24371208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0885328213479047
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