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The Effect of Glycosaminoglycan Stabilization on Tissue Buckling in Bioprosthetic Heart Valves

Bioprosthetic valves are used in thousands of heart valve replacement surgeries. Existing glutaraldehyde-crosslinked bioprosthetic valves fail due to either calcification or degeneration. Glutaraldehyde crosslinking does not stabilize valvular glycosaminoglycans (GAGs). GAGs, predominantly present i...

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Detalhes bibliográficos
Main Authors: Shah, Sagar R., Vyavahare, Naren R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268977/
https://ncbi.nlm.nih.gov/pubmed/18199477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2007.12.00
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