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The Legionella anti-autophagy effector RavZ targets the autophagosome via PI3P- and curvature-sensing motifs
Autophagy is a conserved membrane transport pathway used to destroy pathogenic microbes that access the cytosol of cells. The intracellular pathogen Legionella pneumophila interferes with autophagy by delivering an effector protein, RavZ, into the host cytosol. RavZ acts by cleaving membrane-conjuga...
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| Publicado no: | Dev Cell |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4594837/ https://ncbi.nlm.nih.gov/pubmed/26343456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2015.08.010 |
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