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Systemic Retinaldehyde Treatment Corrects Retinal Oxidative Stress, Rod Dysfunction, and Impaired Visual Performance in Diabetic Mice

PURPOSE: Diabetes appears to induce a visual cycle defect because rod dysfunction is correctable with systemic treatment of the visual cycle chromophore 11-cis-retinaldehyde. However, later studies have found no evidence for visual cycle impairment. Here, we further examined whether photoreceptor dy...

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書誌詳細
出版年:Invest Ophthalmol Vis Sci
主要な著者: Berkowitz, Bruce A., Kern, Timothy S., Bissig, David, Patel, Priya, Bhatia, Ankit, Kefalov, Vladimir J., Roberts, Robin
フォーマット: Artigo
言語:Inglês
出版事項: The Association for Research in Vision and Ophthalmology 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4594469/
https://ncbi.nlm.nih.gov/pubmed/26431483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-16990
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