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Development of an MRI biomarker sensitive to tetrameric visual arrestin 1 and its reduction via light-evoked translocation in vivo

Rod tetrameric arrestin 1 (tet-ARR1), stored in the outer nuclear layer/inner segments in the dark, modulates photoreceptor synaptic activity; light exposure stimulates a reduction via translocation to the outer segments for terminating G-protein coupled phototransduction signaling. Here, we test th...

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書目詳細資料
發表在:FASEB J
Main Authors: Berkowitz, Bruce A., Gorgis, Jawan, Patel, Ankit, Baameur, Faiza, Gurevich, Vsevolod V., Craft, Cheryl M., Kefalov, Vladimir J., Roberts, Robin
格式: Artigo
語言:Inglês
出版: Federation of American Societies for Experimental Biology 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314227/
https://ncbi.nlm.nih.gov/pubmed/25351983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-254953
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