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Influence of lipids on the hydrophobic barrier within the pore of the TWIK-1 K2P channel

Several recent ion channel structures have revealed large side portals, or ‘fenestrations’ at the interface between their transmembrane helices that potentially expose the ion conduction pathway to the lipid core of the bilayer. In a recent study we demonstrated that functional activity of the TWIK-...

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Bibliografiske detaljer
Udgivet i:Channels (Austin)
Main Authors: Aryal, Prafulla, Abd-Wahab, Firdaus, Bucci, Giovanna, Sansom, Mark SP, Tucker, Stephen J
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4594343/
https://ncbi.nlm.nih.gov/pubmed/25487004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/19336950.2014.981987
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