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Influence of lipids on the hydrophobic barrier within the pore of the TWIK-1 K2P channel

Several recent ion channel structures have revealed large side portals, or ‘fenestrations’ at the interface between their transmembrane helices that potentially expose the ion conduction pathway to the lipid core of the bilayer. In a recent study we demonstrated that functional activity of the TWIK-...

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Detalhes bibliográficos
Publicado no:Channels (Austin)
Main Authors: Aryal, Prafulla, Abd-Wahab, Firdaus, Bucci, Giovanna, Sansom, Mark SP, Tucker, Stephen J
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4594343/
https://ncbi.nlm.nih.gov/pubmed/25487004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/19336950.2014.981987
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