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A tale of two CLCs: biophysical insights toward understanding ClC-5 and ClC-7 function in endosomes and lysosomes

The CLC protein family comprises both Cl(−) channels and H(+)-coupled anion transporters. The understanding of the critical role of CLC proteins in a number of physiological functions has greatly contributed to a revision of the classical paradigm that attributed to Cl(−) ions only a marginal role i...

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Detalhes bibliográficos
Publicado no:J Physiol
Autor principal: Zifarelli, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4594289/
https://ncbi.nlm.nih.gov/pubmed/26036722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP270604
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