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A tale of two CLCs: biophysical insights toward understanding ClC-5 and ClC-7 function in endosomes and lysosomes
The CLC protein family comprises both Cl(−) channels and H(+)-coupled anion transporters. The understanding of the critical role of CLC proteins in a number of physiological functions has greatly contributed to a revision of the classical paradigm that attributed to Cl(−) ions only a marginal role i...
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Publicado en: | J Physiol |
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Autor principal: | |
Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
John Wiley & Sons, Ltd
2015
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4594289/ https://ncbi.nlm.nih.gov/pubmed/26036722 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP270604 |
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