Učitavanje...

Structural determinants of interaction, trafficking and function in the ClC-2/MLC1 subunit GlialCAM involved in leukodystrophy

Mutations in the genes encoding the astrocytic protein MLC1, the cell adhesion molecule GlialCAM or the Cl(−) channel ClC-2 underlie human leukodystrophies. GlialCAM binds to itself, to MLC1 and to ClC-2, and directs these proteins to cell–cell contacts. In addition, GlialCAM dramatically activates...

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Bibliografski detalji
Izdano u:J Physiol
Glavni autori: Capdevila-Nortes, Xavier, Jeworutzki, Elena, Elorza-Vidal, Xabier, Barrallo-Gimeno, Alejandro, Pusch, Michael, Estévez, Raúl
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons, Ltd 2015
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4594291/
https://ncbi.nlm.nih.gov/pubmed/26033718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP270467
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