DNA unwinding upon strand-displacement binding of a thymine-substituted polyamide to double-stranded DNA.

It was recently found that polyamide nucleic acid (PNA) analogues consisting of thymines attached to an aminoethylglycine backbone bind strongly and sequence-selectively to adenine sequences of oligonucleotides and double-stranded DNA [Nielsen, P. E., Egholm, M., Berg, R. H. & Buchardt, O. (1991) Sc...

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Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Cherny, D Y, Belotserkovskii, B P, Frank-Kamenetskii, M D, Egholm, M, Buchardt, O, Berg, R H, Nielsen, P E
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1993
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45940/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8383322/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.5.1667
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