DNA unwinding upon strand-displacement binding of a thymine-substituted polyamide to double-stranded DNA.

It was recently found that polyamide nucleic acid (PNA) analogues consisting of thymines attached to an aminoethylglycine backbone bind strongly and sequence-selectively to adenine sequences of oligonucleotides and double-stranded DNA [Nielsen, P. E., Egholm, M., Berg, R. H. & Buchardt, O. (1991...

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Detalhes bibliográficos
Main Authors: Cherny, D Y, Belotserkovskii, B P, Frank-Kamenetskii, M D, Egholm, M, Buchardt, O, Berg, R H, Nielsen, P E
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC45940/
https://ncbi.nlm.nih.gov/pubmed/8383322
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