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Separating myoblast differentiation from muscle cell fusion using IGF-I and the p38 MAP kinase inhibitor SB202190

The p38 MAP kinases play critical roles in skeletal muscle biology, but the specific processes regulated by these kinases remain poorly defined. Here we find that activity of p38α/β is important not only in early phases of myoblast differentiation, but also in later stages of myocyte fusion and myof...

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Publié dans:Am J Physiol Cell Physiol
Auteurs principaux: Gardner, Samantha, Gross, Sean M., David, Larry L., Klimek, John E., Rotwein, Peter
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4593770/
https://ncbi.nlm.nih.gov/pubmed/26246429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00184.2015
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