A stress response p38 MAP kinase inhibitor SB202190 promoted TFEB/TFE3-dependent autophagy and lysosomal biogenesis independent of p38

TFEB (transcription factor EB) and TFE3 (transcription factor E3) are “master regulators” of autophagy and lysosomal biogenesis. The stress response p38 mitogen-activated protein (MAP) kinases affect multiple intracellular responses including inflammation, cell growth, differentiation, cell death, s...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Yang, Chuanbin, Zhu, Zhou, Tong, Benjamin Chun-Kit, Iyaswamy, Ashok, Xie, Wen-Jian, Zhu, Yu, Sreenivasmurthy, Sravan Gopalkrishnashetty, Senthilkumar, Krishnamoorthi, Cheung, King-Ho, Song, Ju-Xian, Zhang, Hong-Jie, Li, Min
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7264467/
https://ncbi.nlm.nih.gov/pubmed/32037305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101445
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