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Evaluation of DOTA-chelated neurotensin analogs with spacer-enhanced biological performance for neurotensin-receptor-1-positive tumor targeting
INTRODUCTION: Neurotensin receptor 1 (NTR1) is overexpressed in many cancers types. Neurotensin (NT), a 13 amino acid peptide, is the native ligand for NTR1 and exhibits high (nM) affinity to the receptor. Many laboratories have been investigating the development of diagnostic and therapeutic radiop...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Nucl Med Biol |
|---|---|
| Prif Awduron: | , , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2015
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4593760/ https://ncbi.nlm.nih.gov/pubmed/26302836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2015.07.010 |
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