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Synthesis and In Vitro/In Vivo Evaluation of Hypoxia-Enhanced (111)In-Bombesin Conjugates for Prostate Cancer Imaging

Receptor-targeted agents, such as BB2r-targeted peptides, have been investigated extensively in preclinical and clinical studies. In an attempt to increase the effectiveness of diagnostic and/or radiotherapeutic agents, we have begun to explore the incorporation of the hypoxia-selective prodrug 2-ni...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhou, Zhengyuan, Wagh, Nilesh K., Ogbomo, Sunny M., Shi, Wen, Jia, Yinnong, Brusnahan, Susan K., Garrison, Jered C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049340/
https://ncbi.nlm.nih.gov/pubmed/23896558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.112.117986
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