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Micropatterning of TCR and LFA-1 ligands reveals complementary effects on cytoskeleton mechanics in T-cells

The formation of the immunological synapse between a T-cell and the antigen-presenting cell (APC) is critically dependent on actin dynamics, downstream of T-cell receptor (TCR) and integrin (LFA-1) signalling. There is also accumulating evidence that mechanical forces, generated by actin polymerizat...

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Detalhes bibliográficos
Publicado no:Integr Biol (Camb)
Main Authors: Tabdanov, Erdem, Gondarenko, Sasha, Kumari, Sudha, Liapis, Anastasia, Dustin, Michael L., Sheetz, Michael P., Kam, Lance C., Iskratsch, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4593733/
https://ncbi.nlm.nih.gov/pubmed/26156536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5ib00032g
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