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Synthesis, antiproliferative activity and possible mechanism of action of novel 2-acetamidobenzamides bearing the 2-phenoxy functionality
Several new 2-(2-phenoxyacetamido)benzamides 17a–v, 21 and 22 were synthesized by stirring in pyridine the acid chlorides 16a–e and the appropriate5-R-4-R(1)-2-aminobenzamide 15a–e and initially evaluated in vitro for antiproliferative activity against the K562 (human chronic myelogenous leukemia) c...
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| Udgivet i: | Bioorg Med Chem |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4593655/ https://ncbi.nlm.nih.gov/pubmed/26344588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2015.08.027 |
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