Synthesis, antiproliferative activity, and mechanism of action of a series of 2-{[(2E)-3-phenylprop-2-enoyl]amino}benzamides

Several new 2-{[(2E)-3-phenylprop-2-enoyl]amino}benzamides 12a–s and 17t–v were synthesized by stirring in pyridine the (E)-3-(2-R1-3-R2-4-R3-phenyl)acrylic acid chlorides 11c–k and 11t–v with the appropriate anthranilamide derivatives 10a–c or the 5-iodoanthranilic acid 13. Some of the synthesized...

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Bibliografiske detaljer
Main Authors:	Raffa, Demetrio, Maggio, Benedetta, Plescia, Fabiana, Cascioferro, Stella, Plescia, Salvatore, Raimondi, Maria Valeria, Daidone, Giuseppe, Tolomeo, Manlio, Grimaudo, Stefania, Di Cristina, Antonietta, Pipitone, Rosaria Maria, Bai, Ruoli, Hamel, Ernest
Format:	Artigo
Sprog:	Inglês
Udgivet:	2011
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3120216/ https://ncbi.nlm.nih.gov/pubmed/21530013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2011.03.067
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Synthesis, antiproliferative activity, and mechanism of action of a series of 2-{[(2E)-3-phenylprop-2-enoyl]amino}benzamides

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