Synthesis, antiproliferative activity, and mechanism of action of a series of 2-{[(2E)-3-phenylprop-2-enoyl]amino}benzamides

Several new 2-{[(2E)-3-phenylprop-2-enoyl]amino}benzamides 12a–s and 17t–v were synthesized by stirring in pyridine the (E)-3-(2-R1-3-R2-4-R3-phenyl)acrylic acid chlorides 11c–k and 11t–v with the appropriate anthranilamide derivatives 10a–c or the 5-iodoanthranilic acid 13. Some of the synthesized...

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Detalhes bibliográficos
Main Authors: Raffa, Demetrio, Maggio, Benedetta, Plescia, Fabiana, Cascioferro, Stella, Plescia, Salvatore, Raimondi, Maria Valeria, Daidone, Giuseppe, Tolomeo, Manlio, Grimaudo, Stefania, Di Cristina, Antonietta, Pipitone, Rosaria Maria, Bai, Ruoli, Hamel, Ernest
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3120216/
https://ncbi.nlm.nih.gov/pubmed/21530013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2011.03.067
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