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The SET Domain Is Essential for Metnase Functions in Replication Restart and the 5’ End of SS-Overhang Cleavage
Metnase (also known as SETMAR) is a chimeric SET-transposase protein that plays essential role(s) in non-homologous end joining (NHEJ) repair and replication fork restart. Although the SET domain possesses histone H3 lysine 36 dimethylation (H3K36me2) activity associated with an improved association...
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Udgivet i: | PLoS One |
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Main Authors: | , , , |
Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
Public Library of Science
2015
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4593633/ https://ncbi.nlm.nih.gov/pubmed/26437079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139418 |
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