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The SET Domain Is Essential for Metnase Functions in Replication Restart and the 5’ End of SS-Overhang Cleavage

Metnase (also known as SETMAR) is a chimeric SET-transposase protein that plays essential role(s) in non-homologous end joining (NHEJ) repair and replication fork restart. Although the SET domain possesses histone H3 lysine 36 dimethylation (H3K36me2) activity associated with an improved association...

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Publicat a:PLoS One
Autors principals: Kim, Hyun-Suk, Kim, Sung-Kyung, Hromas, Robert, Lee, Suk-Hee
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4593633/
https://ncbi.nlm.nih.gov/pubmed/26437079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139418
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