Wird geladen...

Antisense Oligonucleotide-Mediated Transcript Knockdown in Zebrafish

Antisense oligonucleotides (ASOs) are synthetic, single-strand RNA-DNA hybrids that induce catalytic degradation of complementary cellular RNAs via RNase H. ASOs are widely used as gene knockdown reagents in tissue culture and in Xenopus and mouse model systems. To test their effectiveness in zebraf...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Pauli, Andrea, Montague, Tessa G., Lennox, Kim A., Behlke, Mark A., Schier, Alexander F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4593562/
https://ncbi.nlm.nih.gov/pubmed/26436892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139504
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!