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Conserved regulation of Nodal-mediated left-right patterning in zebrafish and mouse
Nodal is the major effector of left-right axis development. In mice, Nodal forms heterodimers with Gdf1 and is inhibited by Cerl2/Dand5 at the node, and by Lefty1 in the lateral plate mesoderm (LPM). Studies in zebrafish have suggested some parallels, but also differences, between left-right pattern...
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| Publicado no: | Development |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Ltd
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6307886/ https://ncbi.nlm.nih.gov/pubmed/30446628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.171090 |
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