Improved OTU-picking using long-read 16S rRNA gene amplicon sequencing and generic hierarchical clustering

BACKGROUND: High-throughput bacterial 16S rRNA gene sequencing followed by clustering of short sequences into operational taxonomic units (OTUs) is widely used for microbiome profiling. However, clustering of short 16S rRNA gene reads into biologically meaningful OTUs is challenging, in part because...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Microbiome
Egile Nagusiak: Franzén, Oscar, Hu, Jianzhong, Bao, Xiuliang, Itzkowitz, Steven H., Peter, Inga, Bashir, Ali
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2015
Gaiak:
Methodology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4593230/
https://ncbi.nlm.nih.gov/pubmed/26434730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40168-015-0105-6
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