Improved OTU-picking using long-read 16S rRNA gene amplicon sequencing and generic hierarchical clustering

BACKGROUND: High-throughput bacterial 16S rRNA gene sequencing followed by clustering of short sequences into operational taxonomic units (OTUs) is widely used for microbiome profiling. However, clustering of short 16S rRNA gene reads into biologically meaningful OTUs is challenging, in part because...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Microbiome
Päätekijät: Franzén, Oscar, Hu, Jianzhong, Bao, Xiuliang, Itzkowitz, Steven H., Peter, Inga, Bashir, Ali
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2015
Aiheet:
Methodology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4593230/
https://ncbi.nlm.nih.gov/pubmed/26434730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40168-015-0105-6
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