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Improved OTU-picking using long-read 16S rRNA gene amplicon sequencing and generic hierarchical clustering
BACKGROUND: High-throughput bacterial 16S rRNA gene sequencing followed by clustering of short sequences into operational taxonomic units (OTUs) is widely used for microbiome profiling. However, clustering of short 16S rRNA gene reads into biologically meaningful OTUs is challenging, in part because...
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| 發表在: | Microbiome |
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| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BioMed Central
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4593230/ https://ncbi.nlm.nih.gov/pubmed/26434730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40168-015-0105-6 |
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