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ACUTE PHASE DEATHS FROM MURINE POLYMICROBIAL SEPSIS ARE CHARACTERIZED BY INNATE IMMUNE SUPPRESSION RATHER THAN EXHAUSTION()

Sepsis, a leading cause of death in the U.S., has poorly understood mechanisms of mortality. To address this, our model of Cecal Ligation and Puncture (CLP) induced sepsis stratifies mice as predicted to Live (Live-P) or Die (Die-P) based on plasma IL-6. Six hours post-CLP, both Live-P and Die-P gro...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Chiswick, Evan L., Mella, Juan R., Bernardo, John, Remick, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592823/
https://ncbi.nlm.nih.gov/pubmed/26371253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500874
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