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ACUTE PHASE DEATHS FROM MURINE POLYMICROBIAL SEPSIS ARE CHARACTERIZED BY INNATE IMMUNE SUPPRESSION RATHER THAN EXHAUSTION()

Sepsis, a leading cause of death in the U.S., has poorly understood mechanisms of mortality. To address this, our model of Cecal Ligation and Puncture (CLP) induced sepsis stratifies mice as predicted to Live (Live-P) or Die (Die-P) based on plasma IL-6. Six hours post-CLP, both Live-P and Die-P gro...

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Bibliografiske detaljer
Udgivet i:J Immunol
Main Authors: Chiswick, Evan L., Mella, Juan R., Bernardo, John, Remick, Daniel
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592823/
https://ncbi.nlm.nih.gov/pubmed/26371253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500874
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