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Spotting the enemy within: Targeted silencing of foreign DNA in mammalian genomes by the Krüppel-associated box zinc finger protein family

Tandem C2H2-type zinc finger proteins (ZFPs) constitute the largest transcription factor family in animals. Tandem-ZFPs bind DNA in a sequence-specific manner through arrays of multiple zinc finger domains that allow high flexibility and specificity in target recognition. In tetrapods, a large propo...

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Detalhes bibliográficos
Publicado no:Mob DNA
Main Authors: Wolf, Gernot, Greenberg, David, Macfarlan, Todd S.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592553/
https://ncbi.nlm.nih.gov/pubmed/26435754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13100-015-0050-8
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