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Preferential retrotransposition in aging yeast mother cells is correlated with increased genome instability

Retrotransposon expression or mobility is increased with age in multiple species and could promote genome instability or altered gene expression during aging. However, it is unclear whether activation of retrotransposons during aging is an indirect result of global changes in chromatin and gene regu...

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Bibliografische gegevens
Gepubliceerd in:DNA Repair (Amst)
Hoofdauteurs: Patterson, Melissa N., Scannapieco, Alison E., Au, Pak Ho, Dorsey, Savanna, Royer, Catherine A., Maxwell, Patrick H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592464/
https://ncbi.nlm.nih.gov/pubmed/26298836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2015.07.004
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