Tissue Transglutaminase Mediated Tumor-Stroma Interaction Promotes Pancreatic Cancer Progression

PURPOSE: Aggressive pancreatic cancer is commonly associated with a dense desmoplastic stroma, which forms a protective niche for cancer cells. The objective of the study was to determine the functions of tissue transglutaminase (TG2), a Ca(2+)-dependent enzyme which crosslinks proteins through tran...

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Bibliografske podrobnosti
izdano v:Clin Cancer Res
Main Authors: Lee, Jiyoon, Condello, Salvatore, Yakubov, Bakhtiyor, Emerson, Robert, Caperell-Grant, Andrea, Hitomi, Kiyotaka, Xie, Jingwu, Matei, Daniela
Format: Artigo
Jezik:Inglês
Izdano: 2015
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592394/
https://ncbi.nlm.nih.gov/pubmed/26041746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-0226
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