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Tissue transglutaminase regulates β-catenin signaling through a c-Src-dependent mechanism
Tissue transglutaminase (TG2) is a multifunctional enzyme involved in protein cross-linking and cell adhesion to fibronectin (FN). In cancer, TG2 induces an epithelial to mesenchymal transition, contributing to metastasis. Because cadherins bind β-catenin at cell-cell junctions, disruption of adhere...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Federation of American Societies for Experimental Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4050431/ https://ncbi.nlm.nih.gov/pubmed/23640056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-222620 |
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