Extracellular Tissue Transglutaminase Activates Noncanonical NF-κB Signaling and Promotes Metastasis in Ovarian Cancer

Tissue transglutaminase (TG2) is a multifunctional protein that binds to fibronectin and exerts protein transamidating activity in the presence of Ca(2+). We previously reported that TG2 is upregulated in ovarian tumors and enhances intraperitoneal (i.p.) metastasis. TG2 is secreted abundantly in ov...

Full description

Saved in:
Bibliographic Details
Main Authors: Yakubov, Bakhtiyor, Chelladurai, Bhadrani, Schmitt, Jordan, Emerson, Robert, Turchi, John J, Matei, Daniela
Format: Artigo
Language:Inglês
Published: Neoplasia Press Inc. 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3664993/
https://ncbi.nlm.nih.gov/pubmed/23730209
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items