Extracellular Tissue Transglutaminase Activates Noncanonical NF-κB Signaling and Promotes Metastasis in Ovarian Cancer

Tissue transglutaminase (TG2) is a multifunctional protein that binds to fibronectin and exerts protein transamidating activity in the presence of Ca(2+). We previously reported that TG2 is upregulated in ovarian tumors and enhances intraperitoneal (i.p.) metastasis. TG2 is secreted abundantly in ov...

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Bibliographische Detailangaben
Hauptverfasser: Yakubov, Bakhtiyor, Chelladurai, Bhadrani, Schmitt, Jordan, Emerson, Robert, Turchi, John J, Matei, Daniela
Format: Artigo
Sprache:Inglês
Veröffentlicht: Neoplasia Press Inc. 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3664993/
https://ncbi.nlm.nih.gov/pubmed/23730209
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