New DNA Methylation Markers for Pancreatic Cancer: Discovery, Tissue Validation, and Pilot Testing in Pancreatic Juice

PURPOSE: Discriminant markers for pancreatic cancer detection are needed. We sought to identify and validate methylated DNA markers for pancreatic cancer using next-generation sequencing unbiased by known targets. EXPERIMENTAL DESIGN: At a referral center, we conducted four sequential case-control s...

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Pubblicato in:Clin Cancer Res
Autori principali: Kisiel, John B., Raimondo, Massimo, Taylor, William R., Yab, Tracy C., Mahoney, Douglas W., Sun, Zhifu, Middha, Sumit, Baheti, Saurabh, Zou, Hongzhi, Smyrk, Thomas C., Boardman, Lisa A., Petersen, Gloria M., Ahlquist, David A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592385/
https://ncbi.nlm.nih.gov/pubmed/26023084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-2469
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