New DNA Methylation Markers for Pancreatic Cancer: Discovery, Tissue Validation, and Pilot Testing in Pancreatic Juice

PURPOSE: Discriminant markers for pancreatic cancer detection are needed. We sought to identify and validate methylated DNA markers for pancreatic cancer using next-generation sequencing unbiased by known targets. EXPERIMENTAL DESIGN: At a referral center, we conducted four sequential case-control s...

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Vydáno v:Clin Cancer Res
Hlavní autoři: Kisiel, John B., Raimondo, Massimo, Taylor, William R., Yab, Tracy C., Mahoney, Douglas W., Sun, Zhifu, Middha, Sumit, Baheti, Saurabh, Zou, Hongzhi, Smyrk, Thomas C., Boardman, Lisa A., Petersen, Gloria M., Ahlquist, David A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592385/
https://ncbi.nlm.nih.gov/pubmed/26023084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-2469
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