New DNA Methylation Markers for Pancreatic Cancer: Discovery, Tissue Validation, and Pilot Testing in Pancreatic Juice

PURPOSE: Discriminant markers for pancreatic cancer detection are needed. We sought to identify and validate methylated DNA markers for pancreatic cancer using next-generation sequencing unbiased by known targets. EXPERIMENTAL DESIGN: At a referral center, we conducted four sequential case-control s...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Kisiel, John B., Raimondo, Massimo, Taylor, William R., Yab, Tracy C., Mahoney, Douglas W., Sun, Zhifu, Middha, Sumit, Baheti, Saurabh, Zou, Hongzhi, Smyrk, Thomas C., Boardman, Lisa A., Petersen, Gloria M., Ahlquist, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592385/
https://ncbi.nlm.nih.gov/pubmed/26023084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-2469
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