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NH125 reduces the level of CPEB3, an RNA binding protein, to promote synaptic GluA2 expression

Neuronal activity can alter the phosphorylation state of eukaryotic elongation factor 2 (eEF2) and thereby regulates protein synthesis. This is thought to be the underlying mechanism for a form of synaptic plasticity that involves changes in the expression of synaptic AMPA type glutamate receptors....

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書目詳細資料
發表在:Neuropharmacology
Main Authors: Bender, Crhistian L., Yang, Qian, Sun, Lu, Liu, Siqiong June
格式: Artigo
語言:Inglês
出版: 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592363/
https://ncbi.nlm.nih.gov/pubmed/25842244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2015.03.017
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