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NH125 reduces the level of CPEB3, an RNA binding protein, to promote synaptic GluA2 expression
Neuronal activity can alter the phosphorylation state of eukaryotic elongation factor 2 (eEF2) and thereby regulates protein synthesis. This is thought to be the underlying mechanism for a form of synaptic plasticity that involves changes in the expression of synaptic AMPA type glutamate receptors....
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| Publicado en: | Neuropharmacology |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4592363/ https://ncbi.nlm.nih.gov/pubmed/25842244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2015.03.017 |
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