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Lipoprotein receptor–related protein 6 is required for parathyroid hormone–induced Sost suppression
Parathyroid hormone (PTH) suppresses the expression of a bone formation inhibitor sclerostin (Sost) in osteocytes by inducing nuclear accumulation of histone deacetylases (HDACs) to inhibit the myocyte enhancer factor 2 (MEF2)-dependent Sost bone enhancer. Previous studies revealed that lipoprotein...
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| Publié dans: | Ann N Y Acad Sci |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4592361/ https://ncbi.nlm.nih.gov/pubmed/25847683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nyas.12750 |
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