Dendritic cells accumulate in the bone marrow of myeloma patients where they protect tumor plasma cells from CD8(+) T-cell killing

Many researchers have speculated that the clinical progression from monoclonal gammopathy of undetermined significance (MGUS) to multiple myeloma (MM) is driven by defects in dendritic cell (DC) function. However, evidence supporting this assumption is controversial, and no mechanism for the putativ...

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Detalles Bibliográficos
Publicado en:Blood
Main Authors: Leone, Patrizia, Berardi, Simona, Frassanito, Maria Antonia, Ria, Roberto, De Re, Valli, Cicco, Sebastiano, Battaglia, Stefano, Ditonno, Paolo, Dammacco, Franco, Vacca, Angelo, Racanelli, Vito
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2015
Assuntos:
Lymphoid Neoplasia
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592278/
https://ncbi.nlm.nih.gov/pubmed/26185130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-01-623975
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