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Dendritic cells accumulate in the bone marrow of myeloma patients where they protect tumor plasma cells from CD8(+) T-cell killing
Many researchers have speculated that the clinical progression from monoclonal gammopathy of undetermined significance (MGUS) to multiple myeloma (MM) is driven by defects in dendritic cell (DC) function. However, evidence supporting this assumption is controversial, and no mechanism for the putativ...
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| Vydáno v: | Blood |
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| Hlavní autoři: | , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society of Hematology
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4592278/ https://ncbi.nlm.nih.gov/pubmed/26185130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-01-623975 |
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