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Dendritic cells accumulate in the bone marrow of myeloma patients where they protect tumor plasma cells from CD8(+) T-cell killing

Many researchers have speculated that the clinical progression from monoclonal gammopathy of undetermined significance (MGUS) to multiple myeloma (MM) is driven by defects in dendritic cell (DC) function. However, evidence supporting this assumption is controversial, and no mechanism for the putativ...

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Vydáno v:Blood
Hlavní autoři: Leone, Patrizia, Berardi, Simona, Frassanito, Maria Antonia, Ria, Roberto, De Re, Valli, Cicco, Sebastiano, Battaglia, Stefano, Ditonno, Paolo, Dammacco, Franco, Vacca, Angelo, Racanelli, Vito
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592278/
https://ncbi.nlm.nih.gov/pubmed/26185130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-01-623975
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